This natural cell process is known as " contact inhibition ."
2.
Thus, contact inhibition of proliferation may be viewed as a reversible form of cell cycle arrest.
3.
The transformed cells will form raised, dense spots on the sample as they grow without contact inhibition.
4.
In fact, YAP overexpression antagonizes contact inhibition.
5.
Many different stimuli apply checkpoint controls including TGFb, DNA damage, contact inhibition, replicative senescence, and growth factor withdrawal.
6.
Cancer cells do not have contact inhibition, and so will continue to grow and divide, regardless of their surroundings.
7.
Migration of keratinocytes over the wound site is stimulated by lack of contact inhibition and by chemicals such as nitric oxide.
8.
Their recent studies have shown that regulation of YAP by the Hippo pathway plays a critical role in cell contact inhibition.
9.
Some immortalised cell lines, despite being able to proliferate indefinitely, still experience contact inhibition, though generally to a lesser extent than normal cell lines.
10.
In the past, cells were thought to enter G 0 by default simply because of proliferation limits such as nutrient deprivation or contact inhibition.
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